Drotrecogin alfa (activated)
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111 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sepsis | D018805 | HP_0100806 | A41.9 | — | 2 | 4 | 5 | 8 | 19 |
| Toxemia | D014115 | — | — | — | 2 | 2 | 2 | 3 | 9 |
| Septic shock | D012772 | — | A48.3 | — | 1 | 2 | 2 | 3 | 8 |
| Blood coagulation disorders | D001778 | EFO_0009314 | D68.9 | — | — | — | 1 | 3 | 4 |
| Hemostatic disorders | D020141 | — | — | — | — | — | 1 | 3 | 4 |
| Shock | D012769 | — | R57.1 | — | 1 | 1 | 2 | — | 4 |
| Hematologic neoplasms | D019337 | — | — | 1 | 1 | — | 1 | — | 3 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | 1 | 2 | 3 |
| Intracranial hemorrhages | D020300 | EFO_0000551 | I62 | — | — | — | 1 | 1 | 2 |
| Infections | D007239 | EFO_0000544 | — | — | — | — | 1 | 1 | 2 |
Show 2 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lymphoma | D008223 | — | C85.9 | 2 | 4 | 3 | — | — | 8 |
| Non-small-cell lung carcinoma | D002289 | — | — | 4 | 4 | 1 | — | — | 7 |
| Leukemia | D007938 | — | C95 | 2 | 3 | 1 | — | 1 | 5 |
| Hemophilia a | D006467 | EFO_0007267 | D66 | — | 2 | 1 | — | 2 | 5 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | 1 | 1 | 1 | — | 2 | 5 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 2 | 1 | — | — | 4 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | — | 1 | 1 | 1 | — | 1 | 3 |
| Chronic renal insufficiency | D051436 | — | N18 | 1 | — | 1 | — | 1 | 3 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | 2 | 1 | — | — | 3 |
| Hemophilia b | D002836 | — | D67 | — | 2 | 1 | — | — | 3 |
Show 9 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 5 | 7 | — | — | 1 | 12 |
| Melanoma | D008545 | — | — | 2 | 9 | — | — | — | 9 |
| Recurrence | D012008 | — | — | 1 | 3 | — | — | 1 | 5 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 2 | 4 | — | — | — | 5 |
| Covid-19 | D000086382 | — | — | 1 | 1 | — | — | 2 | 4 |
| Colorectal neoplasms | D015179 | — | — | 2 | 2 | — | — | — | 3 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 2 | 2 | — | — | — | 3 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | — | 3 | — | — | — | 3 |
| Multiple myeloma | D009101 | — | C90.0 | 2 | 1 | — | — | — | 3 |
| Glioma | D005910 | EFO_0000520 | — | 1 | 2 | — | — | — | 3 |
Show 71 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | 1 | 3 |
| Inflammation | D007249 | MP_0001845 | — | 1 | — | — | — | 2 | 3 |
| Fibrosis | D005355 | — | — | 1 | — | — | — | 1 | 2 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 2 | — | — | — | — | 2 |
| Glioblastoma | D005909 | EFO_0000515 | — | 1 | — | — | — | — | 1 |
| Meningioma | D008579 | EFO_0003098 | D32.9 | 1 | — | — | — | — | 1 |
| Astrocytoma | D001254 | EFO_0000271 | — | 1 | — | — | — | — | 1 |
| Choroid plexus neoplasms | D016545 | EFO_0007206 | — | 1 | — | — | — | — | 1 |
| Oligodendroglioma | D009837 | EFO_0000631 | — | 1 | — | — | — | — | 1 |
| Ganglioglioma | D018303 | — | — | 1 | — | — | — | — | 1 |
Show 11 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | — | — | — | 2 | 2 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 2 | 2 |
| Candidemia | D058387 | EFO_1001282 | — | — | — | — | — | 1 | 1 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 1 | 1 |
| Portal hypertension | D006975 | EFO_0000666 | K76.6 | — | — | — | — | 1 | 1 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | — | — | — | 1 | 1 |
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | — | — | — | 1 | 1 |
| Relapsing-remitting multiple sclerosis | D020529 | EFO_0003929 | — | — | — | — | — | 1 | 1 |
| Sclerosis | D012598 | — | — | — | — | — | — | 1 | 1 |
| Appendicitis | D001064 | EFO_0007149 | K37 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Safety
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Adverse Events
Top Adverse Reactions
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2,371 adverse events reported
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