Drotrecogin alfa (activated)
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Clinical Trials
155 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sepsis | D018805 | EFO_0001420 | A41.9 | — | 2 | 5 | 5 | 9 | 21 |
| Toxemia | D014115 | — | — | — | 1 | 2 | 2 | 3 | 8 |
| Septic shock | D012772 | — | A48.3 | — | 1 | 2 | 2 | 3 | 8 |
| Colorectal neoplasms | D015179 | — | — | 4 | 2 | — | 1 | — | 6 |
| Blood coagulation disorders | D001778 | EFO_0009314 | D68.9 | — | — | — | 1 | 5 | 6 |
| Hematologic neoplasms | D019337 | — | — | 2 | 3 | — | 1 | — | 5 |
| Hemostatic disorders | D020141 | — | — | — | — | — | 1 | 4 | 5 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | 1 | — | 1 | 3 | 5 |
| Shock | D012769 | — | R57.1 | — | — | — | 2 | — | 2 |
| Intracranial hemorrhages | D020300 | EFO_0000551 | I62 | — | — | — | 1 | 1 | 2 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | 5 | 4 | 4 | — | — | 11 |
| Lymphoma | D008223 | — | C85.9 | 3 | 4 | 1 | — | — | 8 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 2 | 2 | 1 | — | 1 | 6 |
| Recurrence | D012008 | — | — | 2 | 3 | 1 | — | 2 | 6 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | 2 | 1 | — | 2 | 5 |
| Hemophilia a | D006467 | EFO_0007267 | D66 | — | 2 | 1 | — | 2 | 5 |
| Protein c deficiency | D020151 | EFO_0009316 | D68.59 | 1 | 2 | 1 | — | 3 | 5 |
| Lung neoplasms | D008175 | — | C34.90 | — | 3 | 2 | — | — | 4 |
| Chronic renal insufficiency | D051436 | — | N18 | 1 | — | 1 | — | 2 | 4 |
| Hepatitis c | D006526 | — | B19.2 | — | 2 | 1 | — | 1 | 3 |
Show 14 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 10 | 3 | — | — | 2 | 12 |
| Melanoma | D008545 | — | — | 4 | 9 | — | — | — | 10 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 4 | 2 | — | — | — | 5 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | 3 | 1 | — | — | — | 4 |
| Multiple myeloma | D009101 | — | C90.0 | 3 | 1 | — | — | — | 4 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | 2 | 2 | — | — | 1 | 4 |
| Leukemia | D007938 | — | C95 | 2 | 1 | — | — | 1 | 4 |
| Healthy volunteers/patients | — | — | — | 3 | 1 | — | — | 1 | 4 |
| Covid-19 | D000086382 | — | U07.1 | 1 | 1 | — | — | 2 | 4 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 1 | 2 | — | — | — | 3 |
Show 52 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neuroblastoma | D009447 | EFO_0000621 | — | 2 | — | — | — | — | 2 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 2 | — | — | — | — | 2 |
| Myeloid leukemia | D007951 | — | C92 | 2 | — | — | — | — | 2 |
| Syndrome | D013577 | — | — | 1 | — | — | — | 1 | 2 |
| Glioblastoma | D005909 | EFO_0000515 | — | 1 | — | — | — | — | 1 |
| Central nervous system neoplasms | D016543 | — | — | 1 | — | — | — | — | 1 |
| Germ cell and embryonal neoplasms | D009373 | — | — | 1 | — | — | — | — | 1 |
| Medulloblastoma | D008527 | — | — | 1 | — | — | — | — | 1 |
| Follicular lymphoma | D008224 | — | C82 | 1 | — | — | — | — | 1 |
| Rhabdoid tumor | D018335 | — | — | 1 | — | — | — | — | 1 |
Show 18 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | — | — | — | 3 | 3 |
| Venous thromboembolism | D054556 | EFO_0004286 | I74 | — | — | — | — | 3 | 3 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 2 | 2 |
| Portal hypertension | D006975 | EFO_0000666 | K76.6 | — | — | — | — | 2 | 2 |
| Sclerosis | D012598 | — | — | — | — | — | — | 2 | 2 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | — | — | 2 | 2 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 2 | 2 |
| Venous thrombosis | D020246 | — | I82.40 | — | — | — | — | 2 | 2 |
| Coronary disease | D003327 | — | — | — | — | — | — | 2 | 2 |
| Coronary artery disease | D003324 | — | I25.1 | — | — | — | — | 2 | 2 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Safety
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Adverse Events
Top Adverse Reactions
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2,371 adverse events reported
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